- Jedi – A game engine developed by LucasArts for Star Wars: Dark Forces and Outlaws
- Kaneva Game Platform – A full featured MMOG engine for independent and professional game development
- Kinetica - A game engine developed by Sony for PlayStation 2.
- KjAPI – A C++ technology to create games and 3D applications for PC computers
- Lithtech – A competing alternative to the Quake, and Unreal engines.
- Lithtech Jupiter Ex – A new generation Lithtech engine developed by Monolith Productions to create the game F.E.A.R.
- Medusa – A C++ 3D game engine developed by Palestar and used in the DarkSpace MMO. It features distributed world simulation, single tool version control and asset realisation, cross-platform compatibility and an integrated client/server network system.
- MMFusion
- Monumental Technology Suite – A MMOG platform, including server and client technology and development / live management tools.
- Multiverse Network – An MMOG platform, including server, client, and tools. (Free for development and use — revenue sharing upon commercial deployment).
- NeoAxis Engine – A game engine and toolkit designed for the creation of game titles for all genres, as well as 3D Visualization and Virtual Reality projects.
- Offset Engine – In development, being used to create fantasy FPS Project Offset (working title)
- Odyssey Engine – Used to create three dimensional computer role-playing games, used in Star Wars: Knights of the Old Republic
- Onyx Engine – Developed by Ubisoft
- Power Render – A general purpose software development kit for games and 3D visualization
- "Q" – A hi tech cross-platform flexible framework and fully featured plugin set for games and other interactive 3D applications with the emphasis on customisability. Developed by Servan Keondjian's Qube Software.
- RAGE – A game engine created by Rockstar Games use it to power their upcoming video games on the Xbox 360 and PlayStation 3
- Realm Crafter – A 3D MMORPG specific game engine with an easy click-and-drop design. Easy to learn scripting language.
- RelentENGINE – A next-generation FPS engine supporting massive destroyable city environments and realistic vehicle control, makes extensive use of shader model 3.
- RenderWare – A very popular 3D API and graphics rendering engine
- Revolution3D – A 3D graphics engine developed by X-Dream Project
- RPG Maker XP – A 2D engine to make top-down and isometric-style role-playing games for Windows.
- SAGE engine – Used to create real-time strategy games
- SCUMM engine – Used in LucasArts graphical adventure games
- Serious Engine – The engine by Croteam used in the epic Serious Sam: The First Encounter and The Second Encounter
- Shark 3D – A middleware from Spinor for computer, video games and realtime 3D applications
- ShiVa – An all-in-one 3D game development platform. The engine (Ston3D) is available for Windows and Macintosh, and can be used inside a web browser.
- Silent Storm engine – A turn-based tactics/tactical RPG game engine, used in Silent Storm.
- Sith – A game engine developed by LucasArts for Jedi Knight: Dark Forces II
- Source engine – A game engine developed by Valve Software for Half-Life 2
- Torque Game Engine – A modified version of a 3D computer game engine originally developed by Dynamix for the 2001 FPS Tribes 2
- Torque Game Engine Advanced – A next-generation 3D game engine support modern GPU hardware and shaders.
- TOSHI – A fourth generation cross platform game engine designed by Blue Tongue Entertainment
- Truevision3d – A 3D game engine using the DirectX API
- Unigine – Cross-platform middleware engine
- Unity – An easy-to-use open-ended 3D game/interactive software engine for web, Windows, Mac OS X, and Nintendo Wii
- Unreal engine – One of the most popular game engines for action games
- Vengeance engine – A video game engine based on the Unreal Engine 2/2.5
- Vicious Engine – Available for Microsoft Windows, Sony PlayStation 2, Microsoft Xbox, and Sony PlayStation Portable
- Visual3D.NET – 3D platform and visual development environment built upon Microsoft .NET 2.0 and XNA Framework for developing for PC, Xbox 360, and Windows Mobile devices using C#, Visual Basic, J#, C++.NET, JScript.NET, IronPython, and visual scripting.
- Virtools – A 3D engine combined with unique high-level development framework, used for game prototyping and rapid developments. Available for Windows, Macintosh, Xbox, PSP
- White Engine – Square-Enix's proprietary seventh generation game engine.
- XnGine – Developed by Bethesda Softworks, one of the first true 3D engines
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